About SS-31 Elamipretide
SS-31, also known as elamipretide, is a small mitochondria-directed tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH2, in which the dimethyltyrosine (Dmt) residue confers antioxidant character and membrane affinity. Its unusual D-amino-acid composition resists conventional proteolysis and supports selective uptake by mitochondria in cell-based experiments. Researchers employ SS-31 to explore cardiolipin remodeling, electron-transport-chain function, reactive-oxygen-species generation, and mitochondrial morphology under metabolic or ischemic stress conditions. The molecule has become a standard tool in mitochondrial research because it links physical membrane interactions to measurable bioenergetic outcomes. Purity demands are exacting: diastereomeric contamination, incomplete amidation, or residual coupling reagents can alter membrane localization and confound oxygen-consumption measurements. Shandong Shengyuan manufactures SS-31 under documented processes and releases each batch only after RP-HPLC purity of 99.8% or higher, LC-MS identity confirmation, and impurity profiling. Lyophilized product is supplied for research use only; not for human or veterinary use.
Research Applications
- Mitochondrial bioenergetics assays
- Cardiolipin interaction studies
- Oxidative stress and ROS research
- Ischemia-reperfusion cell models
- Mitochondrial morphology imaging
Quality & Documentation
Every batch of SS-31 Elamipretide is manufactured under our documented quality system and released with a Certificate of Analysis covering HPLC purity, mass spectrometry identity, peptide content, water content, and endotoxin. The batch code on your vial can be verified online in the COA lookup section of this site.
NAD+ 
MOTS-C 
GHK-CU