Shengyuan Peptides

Catalog / GH Axis Peptides / Ipamorelin

Ipamorelin research peptide — GH Axis Peptides

Ipamorelin

Selective growth hormone secretagogue pentapeptide for studying ghrelin-receptor signaling and GH release without pronounced effects on other pituitary hormones.

CAS Number170851-70-4
Molecular Weight711.9 Da
Purity99.8% (HPLC / MS verified)
CategoryGH Axis Peptides
SequenceAib-His-D-2-Nal-D-Phe-Lys-NH2
Quality metricsHPLC purity, peptide content, and identity are reported separately on the batch COA — see the purity guide.
StorageStore at -20°C in a sealed container with desiccant, away from light; allow vials to equilibrate to room temperature before opening.
Research use only. Not for human or veterinary use. We do not provide dosing guidance or medical advice.
Request a Quote View Batch COA Data

About Ipamorelin

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2, notable for the alpha-aminoisobutyric acid (Aib) residue that confers proteolytic resistance. It binds and activates the ghrelin receptor (GHS-R1a), stimulating growth hormone release in experimental systems, and is valued in research for its relatively selective secretagogue profile compared with broader ghrelin mimetics. Investigators use ipamorelin to dissect GHS-R1a pharmacology, to study growth hormone pulsatility and downstream IGF-1 responses, and to explore ghrelin-receptor involvement in feeding and energy homeostasis. The molecule's unusual residues demand careful synthesis control: enantiomeric contamination of the D-2-Nal and D-Phe positions, or incomplete C-terminal amidation, can dramatically change receptor affinity while producing only subtle mass or retention-time differences. Shandong Shengyuan verifies ipamorelin by RP-HPLC at 99.8% purity or higher, chiral and LC-MS analyses, and peptide-content determination for every batch. Supplied lyophilized, for research use only; not for human or veterinary use.

Research Applications

  • GHS-R1a receptor pharmacology
  • Growth hormone secretagogue assays
  • IGF-1 pathway research
  • Feeding behavior models
  • Pituitary cell secretion research

Quality & Documentation

Every batch of Ipamorelin is manufactured under our documented quality system and released with a Certificate of Analysis covering HPLC purity, mass spectrometry identity, peptide content, water content, and endotoxin. The batch code on your vial can be verified online in the COA lookup section of this site.

Related Products

Tesamorelin Tesamorelin Growth hormone-releasing factor analogue used to investigate pituitary GH secretion, IGF-1 axis signaling, and related metabolic endpoints in research models. Sermorelin Acetate Sermorelin Acetate Synthetic GHRH(1–29) analogue for investigating pituitary growth hormone release and GH/IGF-1 axis regulation in preclinical research. IGF-1 LR3 IGF-1 LR3 Long-acting insulin-like growth factor 1 analogue used to investigate growth-factor signaling, cell proliferation, and anabolic pathways in research systems.