About Melanotan 2 Acetate
Melanotan 2 is a cyclic heptapeptide melanocortin agonist with the sequence Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-NH2, supplied here as the acetate salt. Developed as an alpha-MSH analogue, it exhibits affinity across several melanocortin receptor subtypes and has become a workhorse reagent for melanocortin pharmacology. Researchers apply it in cell-based cAMP assays to rank receptor subtype activation, in studies of melanocyte signaling and pigmentation biology, and in experiments exploring melanocortin control of appetite and energy balance in animal models. The macrocyclic lactam ring is both a strength and a synthesis challenge: epimerization at the D-Phe position, oligomeric by-products, or incomplete N-terminal acetylation can generate impurities with near-identical masses that only orthogonal methods separate reliably. Shandong Shengyuan confirms each batch by RP-HPLC at 99.5% purity or higher, LC-MS sequence and mass verification, and counter-ion quantification to ensure consistent acetate content. Lyophilized material is provided for research use only and is not for human or veterinary use.
Research Applications
- Melanocortin receptor pharmacology
- Pigmentation biology research
- Melanocyte signaling assays
- Appetite regulation models
- Structure-activity relationship studies
Quality & Documentation
Every batch of Melanotan 2 Acetate is manufactured under our documented quality system and released with a Certificate of Analysis covering HPLC purity, mass spectrometry identity, peptide content, water content, and endotoxin. The batch code on your vial can be verified online in the COA lookup section of this site.
PT-141